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Interstate 64 (I-64) is an east–west
Interstate Highway The Dwight D. Eisenhower National System of Interstate and Defense Highways, commonly known as the Interstate Highway System, or the Eisenhower Interstate System, is a network of controlled-access highways that forms part of the National Hi ...
in the
Eastern United States The Eastern United States, often abbreviated as simply the East, is a macroregion of the United States located to the east of the Mississippi River. It includes 17–26 states and Washington, D.C., the national capital. As of 2011, the Eastern ...
. Its western terminus is at
I-70 Interstate 70 (I-70) is a major east–west Interstate Highway in the United States that runs from I-15 near Cove Fort, Utah, to I-695 and Maryland Route 570 (MD 570) in Woodlawn, just outside Baltimore, Maryland. I-70 appr ...
, U.S. Route 40 (US 40), and US 61 in
Wentzville, Missouri Wentzville is an exurb of St. Louis that is located in western St. Charles County, Missouri, United States. As of the 2023 U.S. Census Bureau estimates, the city had a total population of 47,497, making it the 15th largest city in Missouri. Went ...
. Its eastern terminus is at the
Bowers Hill Interchange The Bowers Hill interchange is a large interchange complex where the Hampton Roads Beltway intersects with Interstate 264 (I-264) as well as Military Highway, which carries the three U.S. Highways.https://www.cityofchesapeake.net/1288/Bowers-Hil ...
with I-264 and I-664 at
Bower's Hill Bower's Hill is a community located in the independent city of Chesapeake, Virginia (formerly Norfolk County) in the United States. It is located in the South Hampton Roads region at the northeastern edge of the Great Dismal Swamp, an area ...
in
Chesapeake, Virginia Chesapeake is an independent city in Virginia, United States. At the 2020 census, the population was 249,422, making it the second-most populous city in Virginia, the tenth largest in the Mid-Atlantic, and the 92nd-most populous city in the ...
. I-64 connects
Greater St. Louis Greater St. Louis is the 23rd-largest metropolitan statistical area (MSA) in the United States, the largest in Missouri, and the second-largest in Illinois. Its core city—St. Louis, Missouri—sits in the geographic center of the metro area, ...
, the
Louisville metropolitan area The Louisville metropolitan area is the 43rd largest metropolitan statistical area (MSA) in the United States. It had a population of 1,395,855 in 2020 according to the latest official census, and its principal city is Louisville, Kentucky. T ...
, the
Lexington–Fayette metropolitan area The Lexington-Fayette metropolitan area is the 109th-largest metropolitan statistical area (MSA) in the United States. It was originally formed by the United States Census Bureau in 1950 and consisted solely of Fayette County until 1980, when ...
, the Charleston, WV metropolitan area, the
Greater Richmond Region The Greater Richmond Region, also known as the Richmond metropolitan area or Central Virginia, is a region and metropolitan area in the U.S. state of Virginia, centered on Richmond. The U.S. Office of Management and Budget (OMB) defines the are ...
, and
Hampton Roads Hampton Roads is a body of water in the United States that serves as a wide channel for the James River, James, Nansemond River, Nansemond, and Elizabeth River (Virginia), Elizabeth rivers between Old Point Comfort and Sewell's Point near whe ...
.


Route description

, - , MO , , - , IL , , - , IN , , - , KY , , - , WV , , - , VA , , - , Total , I-64 has concurrencies with
I-55 Interstate 55 (I-55) is a major Interstate Highway in the central United States. As with most primary Interstates that end in a five, it is a major cross-country, north–south route, connecting the Gulf of Mexico to the Great Lakes. The ...
,
I-57 Interstate 57 (I-57) is a north–south Interstate Highway that exists in two segments. It runs through Arkansas, Missouri, and Illinois. I-57 parallels the old Illinois Central Railroad for much of its route north of I-55. The Interstate ...
,
I-75 Interstate 75 (I-75) is a major north–south Interstate Highway System, Interstate Highway in the Great Lakes region, Great Lakes and Southeastern United States, Southeastern regions of the United States. As with most Interstates that end ...
,
I-77 Interstate 77 (I-77) is a north–south Interstate Highway in the Eastern United States. It traverses diverse terrain, from the mountainous state of West Virginia to the rolling farmlands of North Carolina and Ohio. It largely supplants the ...
,
I-81 Interstate 81 (I-81) is a north–south (physically northeast–southwest) Interstate Highway in the eastern part of the United States. Its southern terminus is at I-40 in Dandridge, Tennessee; its northern terminus is on Wellesley Isla ...
, and
I-95 Interstate 95 (I-95) is the main north–south Interstate Highway on the East Coast of the United States, running from U.S. Route 1 (US 1) in Miami, Florida, north to the Houlton–Woodstock Border Crossing between Maine and the ...
. I-64 does not maintain exit number continuity for any of the overlaps, as each of the six north–south routes maintain their exit numbering on their respective overlaps with I-64. Of all the overlaps, I-64 only goes northeast and southwest with I-55 and I-81, while going southeast and northwest with the other Interstates.


Missouri

In Missouri, the stretch was originally labeled as the Daniel Boone Expressway then only as US 40, and, as such, is still known to some locals in
Greater St. Louis Greater St. Louis is the 23rd-largest metropolitan statistical area (MSA) in the United States, the largest in Missouri, and the second-largest in Illinois. Its core city—St. Louis, Missouri—sits in the geographic center of the metro area, ...
as Highway 40, even though the road has been designated as both I-64 and US 40 since 1988. This road is also the southernmost portion of the
Avenue of the Saints The Avenue of the Saints is a highway in the Midwestern United States that connects St. Louis, Missouri, and St. Paul, Minnesota. __TOC__ Route description Missouri The southern end of the Avenue of the Saints is at exit 28A on Interstate ...
. An interchange at Highway N in O'Fallon opened on December 13, 2004. This interchange also accommodates the tie-in of the Route 364 freeway to I-64. In April 2007, construction started to rebuild of I-64 in
St. Louis St. Louis ( , sometimes referred to as St. Louis City, Saint Louis or STL) is an independent city in the U.S. state of Missouri. It lies near the confluence of the Mississippi and the Missouri rivers. In 2020, the city proper had a populatio ...
from Spoede Road to Kingshighway. This project included repaving the entire road, rebuilding the
overpass An overpass, called an overbridge or flyover (for a road only) in the United Kingdom and some other Commonwealth countries, is a bridge, road, railway or similar structure that is over another road or railway. An ''overpass'' and '' underpa ...
es and interchanges, adding a fourth lane between Spoede Road and I-170, and connecting I-64 to I-170 in all directions. Construction resulted in the complete closure of portions of the expressway in 2008 and 2009. In 2008, I-64 was closed from I-270 to I-170, reopening December 15, 2008. Beginning December 15, 2008, I-64 from I-170 to Kingshighway was closed. On December 6, 2009, with a grand opening ceremony and dedication, I-64 was completed in its entire length in Missouri from the
Poplar Street Bridge The Congressman William L. Clay Sr. Bridge, formerly known as the Bernard F. Dickmann Bridge and popularly as the Poplar Street Bridge or PSB, completed in 1967, is a deck girder bridge across the Mississippi River between St. Louis, Missouri, ...
to I-70 in Wentzville. As of December 7, 2009, I-64 is now complete and signed all the way to I-70 in Wentzville. All stoplights have been removed. The portion of I-64 in St. Louis has been named the Jack Buck Memorial Highway, in honor of the late sportscaster.


Illinois

I-64 enters Illinois from St. Louis, Missouri, via the Poplar Street Bridge, where it overlaps I-55 as it crosses the Mississippi River. After crossing the city of East St. Louis and the rest of suburban St. Clair County, the freeway heads southeast through rural
Southern Illinois Southern Illinois is a region of the U.S. state of Illinois comprising the southern third of the state, principally south of Interstate 70. Part of downstate Illinois, it is bordered by the two List of U.S. rivers by discharge, most voluminous ri ...
. Shortly after passing
MidAmerica St. Louis Airport MidAmerica St. Louis Airport – also known as Belleville–St. Louis Airport – is a public use airport next to Scott Air Force Base. It is located east of downtown St. Louis and east of the central business district of Belleville in ...
at exit 23, I-64 enters
Clinton County Clinton County may refer to: *Counties named for George Clinton, first and third Governor of New York, and later the fourth Vice President of the United States: **Clinton County, New York ** Clinton County, Ohio *Counties named for DeWitt Clinton, ...
and then Washington County. After providing access to towns such as Carlyle, Breese,
Nashville Nashville, often known as Music City, is the capital and List of municipalities in Tennessee, most populous city in the U.S. state of Tennessee. It is the county seat, seat of Davidson County, Tennessee, Davidson County in Middle Tennessee, locat ...
, and Centralia, the freeway overlaps I-57 through the
Mount Vernon Mount Vernon is the former residence and plantation of George Washington, a Founding Father, commander of the Continental Army in the Revolutionary War, and the first president of the United States, and his wife, Martha. An American landmar ...
area for approximately . East of Mount Vernon in Illinois, services along I-64 are slim to none. It is an almost completely flat and empty freeway, crossing Jefferson, Wayne, and
White White is the lightest color and is achromatic (having no chroma). It is the color of objects such as snow, chalk, and milk, and is the opposite of black. White objects fully (or almost fully) reflect and scatter all the visible wa ...
counties as it progresses east toward Indiana and the
Evansville, Indiana Evansville is a city in Vanderburgh County, Indiana, United States, and its county seat. With a population of 118,414 at the 2020 United States census, 2020 census, it is Indiana's List of cities in Indiana, third-most populous city after India ...
, area. East of the St. Louis area, there are numerous oilwells dotting the landscape. The section from Illinois Route 127 (IL 127) to I-57 opened on October 4, 1974. The section from IL 161 to IL 127 opened in December 1973. The section in
Metro East The Metro East is an urban area in Southern Illinois, United States that contains the eastern and northern urban, suburban, and exurban areas on the Mississippi River in Greater St. Louis. It encompasses eight Illinois counties and constitutes ...
, except for a short section near I-55/I-70, opened on December 23, 1975. The section from US 460 (later IL 142) to US 45 opened on August 7, 1975.


Indiana

I-64 crosses the Wabash River and enters the state of Indiana. It passes
Griffin The griffin, griffon, or gryphon (; Classical Latin: ''gryps'' or ''grypus''; Late and Medieval Latin: ''gryphes'', ''grypho'' etc.; Old French: ''griffon'') is a -4; we might wonder whether there's a point at which it's appropriate to talk ...
( State Road 69, or SR 69; exit 4) and Poseyville ( SR 165; exit 12) and also passes under nearby SR 68 (no direct interchange serves SR 68, though one can access said route from either SR 165 or SR 65). The Interstate then passes three officially marked exits for
Evansville Evansville is a city in Vanderburgh County, Indiana, United States, and its county seat. With a population of 118,414 at the 2020 census, it is Indiana's third-most populous city after Indianapolis and Fort Wayne, the most populous city in S ...
(SR 65, US 41, and
I-69 Interstate 69 (I-69) is an Interstate Highway in the United States currently consisting of eight unconnected segments. The longest segment runs from Evansville, Indiana, northeast to the Canada–United States border, Canadian border in Po ...
I-164">Interstate_164.html" ;"title="ormerly designated as Interstate 164">I-164 then proceeds through part of the scenic Hoosier National Forest, with exits leading to Dale and Huntingburg, Indiana, Huntingburg ( US 231; exit 57); Santa Claus, Indiana, Santa Claus and Ferdinand, Indiana, Ferdinand ( Indiana State Road 162, SR 162; exit 63);
French Lick French Lick is a town in French Lick Township, Orange County, Indiana, United States. The population was 1,722 at the time of the 2020 census. History French Lick was originally a French trading post built near a spring and salt lick. A for ...
and Tell City ( SR 37; exit 79); and Indiana's first state capital, Corydon ( SR 135; exit 105). Near milepost 61, there is a time change from the
Central Time Zone The North American Central Time Zone (CT) is a time zone in parts of Canada, the United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It ...
(CT; Spencer County) to the
Eastern Time Zone The Eastern Time Zone (ET) is a time zone encompassing part or all of 23 U.S. states, states in the eastern part of the United States, parts of eastern Canada, and the state of Quintana Roo in Mexico. * Eastern Standard Time (EST) is five ...
(ET; Dubois County). Between mileposts 60 and 80, I-64 crosses the CT–ET zone boundary five times. With most timezone changes on highways maintained by the
Indiana Department of Transportation The Indiana Department of Transportation (INDOT) is a governmental agency of the U.S. state of Indiana charged with maintaining and regulating transportation and transportation related infrastructure such as state owned airports, List of number ...
(INDOT), changes in timezone are not usually marked with any roadside signage. The final crossing into the ET zone at the
Perry Perry or pear cider is an alcoholic beverage made from fermented pears, traditionally in England (particularly Gloucestershire, Herefordshire, and Worcestershire), parts of South Wales, France (especially Normandy and Anjou), Canada, Austral ...
Crawford county border, however, is marked with road signage. Between Evansville and New Albany, I-64 intersects a few major north–south arterial highways, such as US 231, SR 37, and SR 135 and offers access to
I-65 Interstate 65 (I-65) is a major north–south interstate highway in the central United States. As with most primary interstates ending in 5, it is a major crosscountry, north–south route, connecting between the Great Lakes and the Gulf ...
to
Indianapolis Indianapolis ( ), colloquially known as Indy, is the List of capitals in the United States, capital and List of municipalities in Indiana, most populous city of the U.S. state of Indiana and the county seat of Marion County, Indiana, Marion ...
via
I-265 Interstate 265 (I-265) is a Interstate Highway partially encircling the Louisville metropolitan area. Starting from I-65 in the southern part of Louisville, it runs through Jefferson County, Kentucky, crosses the Ohio River on the Lewis ...
before crossing into Kentucky on the
Sherman Minton Bridge The Sherman Minton Bridge is a double-deck through arch bridge spanning the Ohio River, carrying I-64 and US 150 over the river between Kentucky and Indiana. The bridge connects the west side of Louisville, Kentucky to downtown New Albany, In ...
. The route in Indiana can be described as being somewhat winding, especially the farther east one travels within the state. The longest straight line distance along the route is the stretch from the SR 65 exit to mikemarker 26, east of US 41. There are many points along the route where the two halves of the highway are nearly apart, especially around the Hoosier National Forest and points to the east. In addition, there are several points, especially in the very sharp valleys along its route in Dubois, Perry, Crawford, and Harrison counties, where the highway towers more than above the surrounding terrain.


Kentucky

I-64 enters
Kentucky Kentucky (, ), officially the Commonwealth of Kentucky, is a landlocked U.S. state, state in the Southeastern United States, Southeastern region of the United States. It borders Illinois, Indiana, and Ohio to the north, West Virginia to the ...
at
Louisville Louisville is the most populous city in the Commonwealth of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. By land area, it is the country's 24th-largest city; however, by populatio ...
, paralleling the
Ohio River The Ohio River () is a river in the United States. It is located at the boundary of the Midwestern and Southern United States, flowing in a southwesterly direction from Pittsburgh, Pennsylvania, to its river mouth, mouth on the Mississippi Riv ...
along the Riverfront Expressway. It intersects with several downtown interchanges before coming to the
Kennedy Interchange The Kennedy Interchange, unofficially, though universally, referred to as Spaghetti Junction, is the intersection of Interstate 64 (I-64), I-65 and I-71 at the northeastern edge of downtown Louisville, Kentucky, United States. It is nam ...
, where it intersects
I-65 Interstate 65 (I-65) is a major north–south interstate highway in the central United States. As with most primary interstates ending in 5, it is a major crosscountry, north–south route, connecting between the Great Lakes and the Gulf ...
and
I-71 Interstate 71 (I-71) is a north–south Interstate Highway in the midwestern and Southeastern United States, southeastern regions of the United States. Its southern terminus is at an interchange with Interstate 64, I-64 and Interstate 65, ...
in a tangle of ramps often referred to as the "Spaghetti Junction". Moving eastward, I-64 passes through Shelbyville, Frankfort, Midway, Lexington,
Winchester Winchester (, ) is a City status in the United Kingdom, cathedral city in Hampshire, England. The city lies at the heart of the wider City of Winchester, a local government Districts of England, district, at the western end of the South Downs N ...
, Mount Sterling, Owingsville, and Morehead, before leaving the state near Ashland at Catlettsburg. It overlaps
I-75 Interstate 75 (I-75) is a major north–south Interstate Highway System, Interstate Highway in the Great Lakes region, Great Lakes and Southeastern United States, Southeastern regions of the United States. As with most Interstates that end ...
as it makes an arc around the northeast of Lexington's urban core, with the exit numbers for I-75 used for the concurrent portion. The two Interstates separate a few miles east of downtown Lexington.


West Virginia

I-64 travels for within the state of
West Virginia West Virginia is a mountainous U.S. state, state in the Southern United States, Southern and Mid-Atlantic (United States), Mid-Atlantic regions of the United States.The United States Census Bureau, Census Bureau and the Association of American ...
, passing by the major cities of Huntington, Beckley, and Lewisburg and directly through the capital city of Charleston. It has only two major junctions within the state:
I-77 Interstate 77 (I-77) is a north–south Interstate Highway in the Eastern United States. It traverses diverse terrain, from the mountainous state of West Virginia to the rolling farmlands of North Carolina and Ohio. It largely supplants the ...
in Charleston and in Beckley. It also crosses the
Kanawha River The Kanawha River ( ) is a tributary of the Ohio River, approximately 97 mi (156 km) long, in the U.S. state of West Virginia. The largest inland waterway in West Virginia, its watershed has been a significant industrial region of th ...
a total of four times in a stretch (twice west of Charleston, immediately before entering the downtown Charleston area, then approximately east of downtown Charleston in Kanawha City). Between I-64's two junctions with I-77, I-64 and I-77 overlap. From the final crossing of the
Kanawha River The Kanawha River ( ) is a tributary of the Ohio River, approximately 97 mi (156 km) long, in the U.S. state of West Virginia. The largest inland waterway in West Virginia, its watershed has been a significant industrial region of th ...
east of Charleston to their split at exit 40 south of Beckley, the two Interstates are tolled, forming a part of the
West Virginia Turnpike Interstate 77 (I-77) in the US state of West Virginia is a major north–south Interstate Highway. It extends for between Bluefield, West Virginia, Bluefield at the Virginia state line and Williamstown, West Virginia, Williamstown at the ...
. While the two expressways overlap, the exit signs are those for I-77. Thus, eastbound travelers entering from Kentucky will see exit numbers increase until exit 60, at which time I-77's exit numbers are used, decreasing from exit 100.


Virginia

I-64 in
Virginia Virginia, officially the Commonwealth of Virginia, is a U.S. state, state in the Southeastern United States, Southeastern and Mid-Atlantic (United States), Mid-Atlantic regions of the United States between the East Coast of the United States ...
runs east–west through central Virginia from West Virginia via Covington, Lexington, Staunton, and
Charlottesville Charlottesville, colloquially known as C'ville, is an independent city in Virginia, United States. It is the seat of government of Albemarle County, which surrounds the city, though the two are separate legal entities. It is named after Quee ...
to
Richmond Richmond most often refers to: * Richmond, British Columbia, a city in Canada * Richmond, California, a city in the United States * Richmond, London, a town in the London Borough of Richmond upon Thames, England * Richmond, North Yorkshire, a town ...
. From Lexington to Staunton, it overlaps I-81 (using I-81 exit numbers). In Richmond, it overlaps I-95. From Richmond, I-64 continues southeasterly through
Newport News Newport News () is an independent city in southeastern Virginia, United States. At the 2020 census, the population was 186,247. Located in the Hampton Roads region, it is the fifth-most populous city in Virginia and 140th-most populous city i ...
and
Hampton Hampton may refer to: Places Australia *Hampton bioregion, an IBRA biogeographic region in Western Australia * Hampton, New South Wales *Hampton, Queensland, a town in the Toowoomba Region * Hampton, Victoria ** Hampton railway station, Melbour ...
to the
Hampton Roads Bridge–Tunnel The Hampton Roads Bridge–Tunnel (HRBT) is a Hampton Roads crossing for Interstate 64 (I-64) and US Route 60 (US 60). It is a four-lane facility comprising bridges, trestles, artificial islands, and tunnels under the main sh ...
and then through
Norfolk Norfolk ( ) is a Ceremonial counties of England, ceremonial county in England, located in East Anglia and officially part of the East of England region. It borders Lincolnshire and The Wash to the north-west, the North Sea to the north and eas ...
and a small portion of
Virginia Beach Virginia Beach (colloquially VB) is the List of cities in Virginia, most populous city in the Commonwealth (U.S. state), U.S. commonwealth of Virginia. The city is located on the Atlantic Ocean at the mouth of the Chesapeake Bay in southeaster ...
to end in
Chesapeake Chesapeake most often refers to: *Chesapeake people, a Native American tribe also known as the Chesepian *Chesapeake Bay *Delmarva Peninsula, also known as the Chesapeake Peninsula Chesapeake may also refer to: Populated places In Virginia * ...
. I-64 itself does not reach the
Oceanfront A coast (coastline, shoreline, seashore) is the land next to the sea or the line that forms the boundary between the land and the ocean or a lake. Coasts are influenced by the topography of the surrounding landscape and by aquatic erosion, su ...
area of Virginia Beach, as it continues through the western portion of Virginia Beach as part of the circumferential
Hampton Roads Beltway The Hampton Roads Beltway is a loop of Interstate 64 and Interstate 664, which links the communities of the Virginia Peninsula and South Hampton Roads which surround the body of water known as Hampton Roads and comprise much of the region o ...
. At its terminus, eastbound I-64 runs over westbound (and westbound I-64 eastbound) as the route forms a fishhook around Norfolk. I-264 intersects the beltway, providing access to other parts of Norfolk and Chesapeake and extending east to the Oceanfront. Access to the Oceanfront area is accomplished from I-64 via a portion of I-264, a roadway originally built as the Virginia Beach Expressway, funded by tolls to retire
revenue bond A revenue bond is a special type of municipal bond distinguished by its guarantee of repayment solely from revenues generated by a specified revenue-generating entity associated with the purpose of the bonds, rather than from a tax. Unlike gener ...
s.


History

Elements of I-64, such as the Sherman Minton bridge over the Ohio River on the Indiana–Kentucky border, were completed by the early 1960s. The Interstate was complete between St. Louis and Charleston with the completion of the 9th Street overpass in Louisville in December 1976. In Virginia, the proposed southern route between Clifton Forge and Richmond called for the Interstate to follow from Richmond via US 360 and US 460, via Lynchburg to Roanoke and US 220 from Roanoke to Clifton Forge, then west following US 60 into West Virginia. The initial 1957 recommendation by a state-retained engineering consultant was for the northern route, but, due in large part to the efforts of a Virginia Senator Mosby Perrow Jr. from Lynchburg, the state changed the location to the southern route in 1959. Despite assurances from the federal government that the route would be decided by the state, Virginia's 1959 decision was overturned in favor of the northern route through Charlottesville. I-64 had a proposed routing around the US 50 corridor in Illinois when the Interstates were first planned. Local pressure pushed the routing closer to the US 460 corridor because of the cheaper cost and shorter mileage compared to the original routing, but not before construction was started on a short section that is now US 50 between
Vincennes, Indiana Vincennes is a city in, and the county seat of, Knox County, Indiana, United States. It is located on the lower Wabash River in the southwestern part of the state, nearly halfway between Evansville and Terre Haute. It was founded in 1732 by F ...
, and
Lawrenceville, Illinois Lawrenceville is a city in and the county seat of Lawrence County, Illinois, United States, located along the Embarras River. The population was 4,348 at the 2010 census. Lawrenceville is located in southeast Illinois, northwest of Vincennes, ...
. It is also worth noting that the apparent route of I-64 would have taken it through the southern end of Carlyle Lake which was also under construction at this time. I-64 signs started going up in August 1987 on the US 40 freeway in St. Louis. This change was made in part due to truck drivers deliberately using US 40 to avoid mandatory fines for overweight trucks.St. Louis Post-Dispatch. August 16, 1987. On September 9, 2011, the
Sherman Minton Bridge The Sherman Minton Bridge is a double-deck through arch bridge spanning the Ohio River, carrying I-64 and US 150 over the river between Kentucky and Indiana. The bridge connects the west side of Louisville, Kentucky to downtown New Albany, In ...
was closed down by Indiana Governor
Mitch Daniels Mitchell Elias Daniels Jr. (born April 7, 1949) is an American Academic administration, academic administrator, businessman, author, and retired politician who served as the 49th governor of Indiana from 2005 to 2013. A Republican Party (United ...
after construction crews found cracks in the main load bearing structural element. Mainline traffic was redirected to
I-265 Interstate 265 (I-265) is a Interstate Highway partially encircling the Louisville metropolitan area. Starting from I-65 in the southern part of Louisville, it runs through Jefferson County, Kentucky, crosses the Ohio River on the Lewis ...
, then south on
I-65 Interstate 65 (I-65) is a major north–south interstate highway in the central United States. As with most primary interstates ending in 5, it is a major crosscountry, north–south route, connecting between the Great Lakes and the Gulf ...
across the
John F. Kennedy Memorial Bridge The John F. Kennedy Memorial Bridge is a six-lane, single-deck cantilever bridge that carries southbound Interstate 65 across the Ohio River, connecting Louisville, Kentucky and Jeffersonville, Indiana. The main span is (two spans) and the b ...
before rejoining I-64 at the
Kennedy Interchange The Kennedy Interchange, unofficially, though universally, referred to as Spaghetti Junction, is the intersection of Interstate 64 (I-64), I-65 and I-71 at the northeastern edge of downtown Louisville, Kentucky, United States. It is nam ...
in Louisville. Repairs were completed in a few months later, and the Sherman Minton Bridge reopened at 11:50 pm on February 17, 2012.


Junction list

;Missouri : in Wentzville. I-64/US 40 travels concurrently to
East St. Louis, Illinois East St. Louis, also known as ESTL, is a city in St. Clair County, Illinois, United States. It is directly across the Mississippi River from downtown St. Louis, Missouri, and the Gateway Arch National Park. East St. Louis is in the Metro East ...
. I-64/US 61 travels concurrently to the Frontenac
Ladue Ladue is an inner-ring suburb of St. Louis, located in St. Louis County, Missouri. As of the 2020 census, the city had a population of 8,989. Ladue has the highest median household income of any city in Missouri with a population over 1,000. Ge ...
city line. : in Town and Country : on the Frontenac–Ladue city line : in Richmond Heights : in
St. Louis St. Louis ( , sometimes referred to as St. Louis City, Saint Louis or STL) is an independent city in the U.S. state of Missouri. It lies near the confluence of the Mississippi and the Missouri rivers. In 2020, the city proper had a populatio ...
. I-55/I-64 travels concurrently to East, St. Louis, Illinois. ;Illinois : in East St. Louis : in Caseyville. I-64/US 50 travels concurrently to O'Fallon. : in Richview : in
Mount Vernon Mount Vernon is the former residence and plantation of George Washington, a Founding Father, commander of the Continental Army in the Revolutionary War, and the first president of the United States, and his wife, Martha. An American landmar ...
. The highways travel concurrently to south-southwest of Mount Vernon. : north of Mill Shoals ;Indiana : west-southwest of Warrenton : west-northwest of
Elberfeld Elberfeld is a municipal subdivision of the Germany, German city of Wuppertal; it was an independent town until 1929. History The first official mentioning of the geographic area on the banks of today's Wupper River as "''elverfelde''" was ...
. Former Junction of Interstate 164 : in Dale : west of New Albany. The highways travel concurrently to
Louisville, Kentucky Louisville is the List of cities in Kentucky, most populous city in the Commonwealth of Kentucky, sixth-most populous city in the Southeastern United States, Southeast, and the list of United States cities by population, 27th-most-populous city ...
. : in New Albany ;Kentucky : in Louisville : in Louisville : in Louisville : in Louisville : in Louisville : on the Middletown–Louisville city line : in Frankfort : southeast of Frankfort : northwest of Lexington : in Lexington. The highways travel concurrently through Lexington. : in Lexington : northeast of
Winchester Winchester (, ) is a City status in the United Kingdom, cathedral city in Hampshire, England. The city lies at the heart of the wider City of Winchester, a local government Districts of England, district, at the western end of the South Downs N ...
: in Mt. Sterling : northeast of Mt. Sterling : east-southeast of Owingsville : northeast of Olive Hill : in Coalton : south-southwest of Catlettsburg ;West Virginia : in Kenova. The highways travel concurrently to Huntington. : in Barboursville : in
Teays Valley Teays Valley ( ) is a census-designated place in Putnam County, West Virginia, United States. The population was 14,350 at the 2020 census. Located about west of Charleston and east of Huntington, it is part of the Huntington–Ashland met ...
: in South Charleston : in Charleston. The highways travel concurrently through Charleston. : in Charleston : in Charleston. The highways travel concurrently to southeast of Crab Orchard. : north of Chelyan : south-southeast of
Crawley Crawley () is a town and Borough status in the United Kingdom, borough in West Sussex, England. It is south of London, north of Brighton and Hove, and north-east of the county town of Chichester. Crawley covers an area of and had a populat ...
: in Lewisburg : east of White Sulphur Springs : east-southeast of White Sulphur Springs. The highways travel concurrently to
Callaghan, Virginia Callaghan is an Unincorporated community and census-designated place (CDP) in Alleghany County, Virginia, United States. The population as of the 2010 Census was 348. Humpback Covered Bridge and Wood Hall are listed on the U.S. National Regi ...
. ;Virginia : in Mallow. I-64/US 60 travels concurrently to north-northwest of Lexington. I-64/US 220 travels concurrently to east-northeast of Clifton Forge. : in East Lexington : east of East Lexington. The highways travel concurrently to Jolivue. : northeast of East Lexington : in Greenville : in Waynesboro : in
Rockfish Gap Rockfish Gap is a wind gap located in the Blue Ridge Mountains between Charlottesville and Waynesboro, Virginia, United States, through Afton Mountain, which is frequently used to refer to the gap. Joining the Shenandoah Valley to the Piedmont ...
: in Yancey Mills : west-southwest of
Charlottesville Charlottesville, colloquially known as C'ville, is an independent city in Virginia, United States. It is the seat of government of Albemarle County, which surrounds the city, though the two are separate legal entities. It is named after Quee ...
: east-southeast of Charlottesville : north-northeast of Zion Crossroads : northeast of Gum Spring : in Short Pump : in Innsbrook : in
Dumbarton Dumbarton (; , or ; or , meaning 'fort of the Britons (historical), Britons') is a town in West Dunbartonshire, Scotland, on the north bank of the River Clyde where the River Leven, Dunbartonshire, River Leven flows into the Clyde estuary. ...
: in Dumbarton : in
Richmond Richmond most often refers to: * Richmond, British Columbia, a city in Canada * Richmond, California, a city in the United States * Richmond, London, a town in the London Borough of Richmond upon Thames, England * Richmond, North Yorkshire, a town ...
: in Richmond. The highways travel concurrently through Richmond. : in Richmond : on the boundary of Richmond with East Highland Park : east of Sandston : in
Newport News Newport News () is an independent city in southeastern Virginia, United States. At the 2020 census, the population was 186,247. Located in the Hampton Roads region, it is the fifth-most populous city in Virginia and 140th-most populous city i ...
: in
Hampton Hampton may refer to: Places Australia *Hampton bioregion, an IBRA biogeographic region in Western Australia * Hampton, New South Wales *Hampton, Queensland, a town in the Toowoomba Region * Hampton, Victoria ** Hampton railway station, Melbour ...
: in Hampton : in Hampton. The highways travel concurrently to
Norfolk Norfolk ( ) is a Ceremonial counties of England, ceremonial county in England, located in East Anglia and officially part of the East of England region. It borders Lincolnshire and The Wash to the north-west, the North Sea to the north and eas ...
: in Norfolk : in Norfolk : in Norfolk : in
Chesapeake Chesapeake most often refers to: *Chesapeake people, a Native American tribe also known as the Chesepian *Chesapeake Bay *Delmarva Peninsula, also known as the Chesapeake Peninsula Chesapeake may also refer to: Populated places In Virginia * ...
. I-64/US 17 travels concurrently through Chesapeake. : in Chesapeake : in Chesapeake


Auxiliary routes

* : Former spur to
Evansville, Indiana Evansville is a city in Vanderburgh County, Indiana, United States, and its county seat. With a population of 118,414 at the 2020 United States census, 2020 census, it is Indiana's List of cities in Indiana, third-most populous city after India ...
, known as the Robert D. Orr Highway, became
I-69 Interstate 69 (I-69) is an Interstate Highway in the United States currently consisting of eight unconnected segments. The longest segment runs from Evansville, Indiana, northeast to the Canada–United States border, Canadian border in Po ...
in 2014. * : Loop around
Louisville, Kentucky Louisville is the List of cities in Kentucky, most populous city in the Commonwealth of Kentucky, sixth-most populous city in the Southeastern United States, Southeast, and the list of United States cities by population, 27th-most-populous city ...
; also called the Georgia Davis Powers/Shawnee Expressway west of the
Dixie Highway Dixie Highway was a United States auto trail first planned in 1914 to connect the Midwest with the South. It was part of a system and was expanded from an earlier Miami to Montreal highway. The final system is better understood as a network o ...
( US 31W) exit and the Watterson Expressway east of US 31W/Dixie Highway * , , , : All serving the
Hampton Roads Hampton Roads is a body of water in the United States that serves as a wide channel for the James River, James, Nansemond River, Nansemond, and Elizabeth River (Virginia), Elizabeth rivers between Old Point Comfort and Sewell's Point near whe ...
region in
Virginia Virginia, officially the Commonwealth of Virginia, is a U.S. state, state in the Southeastern United States, Southeastern and Mid-Atlantic (United States), Mid-Atlantic regions of the United States between the East Coast of the United States ...
.


References


External links


Indiana Highway Ends: I-64

Illinois Highway Ends: I-64


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